The Origin and Immune Recognition of Tumor-Specific Antigens

The Origin and Immune Recognition of Tumor-Specific Antigens

The dominant paradigm holds that spontaneous and therapeutically induced anti-tumor responses are mediated mainly by CD8 T cells and directed against tumor-specific antigens (TSAs). The presence of specific TSAs on cancer cells can only be proven by mass spectrometry analyses. Bioinformatic predicti...

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Bibliographic Details
Main Authors: Anca Apavaloaei, Marie-Pierre Hardy, Pierre Thibault, Claude Perreault
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
antigen processing and presentation
cancer immunotherapy
cross-priming
immunogenicity
major histocompatibility complex
T lymphocyte
Online Access:https://www.mdpi.com/2072-6694/12/9/2607

Internet

https://www.mdpi.com/2072-6694/12/9/2607

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