Implication of the IL-10-Expression Signature in the Pathogenicity of Leptospira-Infected Macrophages

Implication of the IL-10-Expression Signature in the Pathogenicity of Leptospira-Infected Macrophages

ABSTRACT Leptospirosis, an emerging infectious disease caused by pathogenic Leptospira spp., occurs in ecoregions with heavy rainfall and has public health implications. Macrophages are the major anti-Leptospira phagocytes that infiltrate the kidneys during renal leptospirosis, which is caused by le...

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Main Authors: Li-Fang Chou, Ting-Wen Chen, Huang-Yu Yang, Ya-Chung Tian, Ming-Yang Chang, Cheng-Chieh Hung, Chih-Ho Lai, Shen-Hsing Hsu, Chung-Ying Tsai, Yi-Ching Ko, Jang-Hau Lian, Chih-Wei Yang
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
bone marrow-derived macrophage
IL-10
Leptospira spp.
macrophage activation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02595-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.02595-21

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