Enrolment patterns in a randomized controlled trial of probiotics in critically ill patients: a retrospective analysis of the PROSPECT trial

Enrolment patterns in a randomized controlled trial of probiotics in critically ill patients: a retrospective analysis of the PROSPECT trial

Abstract Background Understanding site-related factors that influence enrolment within multicenter randomized controlled trials (RCT) may help reduce trial delays and cost over-runs and prevent early trial discontinuation. In this analysis of PROSPECT (Probiotics: Prevention of Severe Pneumonia and...

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Bibliographic Details
Main Authors: Alyson Takaoka, Jennie Johnstone, François Lauzier, Diane Heels-Ansdell, Megan Davis, Nicole Zytaruk, Erick Duan, Joanna Dionne, Lois Saunders, Yaseen M. Arabi, John Marshall, Lehana Thabane, France Clarke, Lori Hand, Marie-Helene Masse, Bram Rochwerg, Lauralyn McIntyre, Martin Girard, Andreas Freitag, Tim Karachi, Deborah J. Cook, For The PROSPECT Investigators, The Canadian Critical Care Trials Group
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Trials
Subjects:
Randomized trial
Critical illness
Enrolment
Screening
Online Access:https://doi.org/10.1186/s13063-024-08701-w

Internet

https://doi.org/10.1186/s13063-024-08701-w

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