Butafenacil: A positive control for identifying anemia- and variegate porphyria-inducing chemicals
Butafenacil is an herbicide that inhibits protoporphyrinogen oxidase (PPOX), an enzyme that catalyzes oxidation of protoporphyrinogen IX to protoporphyrin IX during chlorophyll and heme biosynthesis. Based on a high-content screen, we previously identified butafenacil as a potent inducer of anemia i...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-01-01
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Series: | Toxicology Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750015300263 |