Tirzepatide prevents neurodegeneration through multiple molecular pathways

Tirzepatide prevents neurodegeneration through multiple molecular pathways

Abstract Background Several evidence demonstrated that glucagon-like peptide 1 receptor agonists (GLP1-RAs) reduce the risk of dementia in type 2 diabetes patients by improving memory, learning, and overcoming cognitive impairment. In this study, we elucidated the molecular processes underlying the...

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Bibliographic Details
Main Authors: Rosaria Anna Fontanella, Puja Ghosh, Ada Pesapane, Fatemeh Taktaz, Armando Puocci, Martina Franzese, Maria Federica Feliciano, Giovanni Tortorella, Lucia Scisciola, Eduardo Sommella, Concetta Ambrosino, Giuseppe Paolisso, Michelangela Barbieri
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
Neurodegeneration
Diabetes mellitus type 2
Neuronal growth
Neurodifferentiation
Insulin resistance
Glucose homeostasis
Online Access:https://doi.org/10.1186/s12967-024-04927-z

Internet

https://doi.org/10.1186/s12967-024-04927-z

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