Missense Mutations in Cancer Predisposing Genes: Can We Make Sense of Them?
<p>Abstract</p> <p>In the analysis of genes associated with predispositions to malignancy the causative status of mutations can be made relatively easily where it is obvious that there is a clear disruption in the coding sequence of the gene. Difficulties arise, however, if missens...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2005-08-01
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Series: | Hereditary Cancer in Clinical Practice |
Subjects: | |
Online Access: | http://www.hccpjournal.com/content/3/3/123 |