Sirtuin 1 in Endothelial Dysfunction and Cardiovascular Aging

Sirtuin 1 in Endothelial Dysfunction and Cardiovascular Aging

Sirtuin 1 (SIRT1) is a histone deacetylase belonging to the family of Sirtuins, a class of nicotinamide adenine dinucleotide (NAD+)-dependent enzymes with multiple metabolic functions. SIRT1 localizes in the nucleus and cytoplasm, and is implicated in the regulation of cell survival in response to s...

Full description

Bibliographic Details
Main Authors: Stefano Ministrini, Yustina M. Puspitasari, Georgia Beer, Luca Liberale, Fabrizio Montecucco, Giovanni G. Camici
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
sirtuin (SIRT1)
aging–old age–seniors
eNOS (endothelial nitric oxide synthase)
inflammaging
endothelial (dys)function
atherosclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.733696/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.733696/full

Similar Items