Increase in repulsive guidance molecule-a (RGMa) in lacunar and cortical stroke patients is related to the severity of the insult

Increase in repulsive guidance molecule-a (RGMa) in lacunar and cortical stroke patients is related to the severity of the insult

Abstract Repulsive guidance molecule-a (RGMa) inhibits angiogenesis and increases inflammation. Animal models of cerebral ischemia have shown that an increased expression of RGMa leads to larger infarction and its inhibition attenuates effects of ischemia. We report on the relationship of RGMa to st...

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Bibliographic Details
Main Authors: Aijaz Parray, Naveed Akhtar, Ghulam Jeelani Pir, Sajitha V. Pananchikkal, Raheem Ayadathil, Fayaz Ahmad Mir, Reny Francis, Ahmed Own, Ashfaq Shuaib
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24481-2

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https://doi.org/10.1038/s41598-022-24481-2

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