Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1β Release by Pulmonary Epithelial Cells

Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1β Release by Pulmonary Epithelial Cells

Phosphocholine-modified bacterial cell wall components are virulence factors enabling immune evasion and permanent colonization of the mammalian host, by mechanisms that are poorly understood. Recently, we demonstrated that free phosphocholine (PC) and PC-modified lipooligosaccharides (PC-LOS) from...

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Bibliographic Details
Main Authors: Katrin Richter, Christian Koch, Alexander Perniss, Philipp M. Wolf, Elke K. H. Schweda, Sven Wichmann, Sigrid Wilker, Ilona Magel, Michael Sander, J. Michael McIntosh, Winfried Padberg, Veronika Grau
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
A549
Calu-3
CHRNA7
CHRNA9
CHRNA10
immune evasion
inflammasome
lung
nicotinic acetylcholine receptor
phosphocholine-modification
Online Access:http://www.mdpi.com/1420-3049/23/8/1979

Internet

http://www.mdpi.com/1420-3049/23/8/1979

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