Evaluating the stability of host-reference gene expression and simultaneously quantifying parasite burden and host immune responses in murine malaria
Abstract The efficacy of pre-erythrocytic stage malaria antigens or vaccine platforms is routinely assessed in murine models challenged with Plasmodium sporozoites. Relative liver-stage parasite burden is quantified using reverse transcription quantitative PCR (RTqPCR), which relies on constitutivel...
| Main Authors: | , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Nature Portfolio
2023-11-01
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| 叢編: | Scientific Reports |
| 在線閱讀: | https://doi.org/10.1038/s41598-023-48066-9 |