Integrative small and long RNA omics analysis of human healing and nonhealing wounds discovers cooperating microRNAs as therapeutic targets

Integrative small and long RNA omics analysis of human healing and nonhealing wounds discovers cooperating microRNAs as therapeutic targets

MicroRNAs (miR), as important epigenetic control factors, reportedly regulate wound repair. However, our insufficient knowledge of clinically relevant miRs hinders their potential therapeutic use. For this, we performed paired small and long RNA-sequencing and integrative omics analysis in human tis...

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Bibliographic Details
Main Authors: Zhuang Liu, Letian Zhang, Maria A Toma, Dongqing Li, Xiaowei Bian, Irena Pastar, Marjana Tomic-Canic, Pehr Sommar, Ning Xu Landén
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-08-01
Series:eLife
Subjects:
microRNA
regulatory network
wound healing
chronic wound
venous ulcer
Online Access:https://elifesciences.org/articles/80322

Internet

https://elifesciences.org/articles/80322

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