A preliminary study on the impact of nutrient stress induction on drug cytotoxicity in glioblastoma cells and fibroblasts

A preliminary study on the impact of nutrient stress induction on drug cytotoxicity in glioblastoma cells and fibroblasts

Abstract Background Nutrient stress (NS), one of the hallmarks of the tumour microenvironment, can render cancer cells tolerant to cytotoxicity. Fibroblasts, on the other hand, have cancer cell-like traits, such as plasticity and resiliency. Hence, this study aimed to evaluate the cytotoxicity of th...

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Bibliographic Details
Main Authors: Siti Nazihahasma Hassan, Abdul Aziz Mohamed Yusoff, Zamzuri Idris, Norhanani Mohd Redzwan, Farizan Ahmad
Format: Article
Language:English
Published: SpringerOpen 2024-04-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Nutrient stress
Drug cytotoxicity
Human glioblastoma cells
Fibroblasts
Azithromycin
Doxycycline
Online Access:https://doi.org/10.1186/s43094-024-00637-x

Internet

https://doi.org/10.1186/s43094-024-00637-x

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