Comparative histopathological analysis of age‐associated intervertebral disc degeneration in CD‐1 and C57BL/6 mice: Anatomical and sex‐based differences

Abstract Background Intervertebral disc (IVD) degeneration is a major contributor to back pain and disability. The cause of IVD degeneration is multifactorial, with no disease‐modifying treatments. Mouse models are commonly used to study IVD degeneration; however, the effects of anatomical location,...

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Bibliographic Details
Main Authors: Jeffrey L. Hutchinson, Matthew A. Veras, Meghan E. Serjeant, Matthew R. McCann, Ashley L. Kelly, Diana Quinonez, Frank Beier, Cheryle A. Séguin
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:JOR Spine
Subjects:
Online Access:https://doi.org/10.1002/jsp2.1298