Attenuated Salmonella carrying siRNA-PD-L1 and radiation combinatorial therapy induces tumor regression on HCC through T cell-mediated immuno-enhancement

Attenuated Salmonella carrying siRNA-PD-L1 and radiation combinatorial therapy induces tumor regression on HCC through T cell-mediated immuno-enhancement

Abstract Hepatocellular carcinoma (HCC), the most prevalent type of aggressive liver cancer, accounts for the majority of liver cancer diagnoses and fatalities. Despite recent advancements in HCC treatment, it remains one of the deadliest cancers. Radiation therapy (RT) is among the locoregional the...

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Bibliographic Details
Main Authors: Huijie Jia, Pengkun Wei, Shijie Zhou, Yuanyuan Hu, Chunjing Zhang, Lirui Liang, Bingqing Li, Zerui Gan, Yuanling Xia, Hanyu Jiang, Mingguang Shao, Sheng Guo, Zishan Yang, Jiateng Zhong, Feng Ren, Huiyong Zhang, Yongxi Zhang, Tiesuo Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01603-x

Internet

https://doi.org/10.1038/s41420-023-01603-x

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