A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: From genomic characterization to high‐throughput field detection

A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: From genomic characterization to high‐throughput field detection

Abstract By altering gene expression and creating paralogs, genomic amplifications represent a key component of short‐term adaptive processes. In insects, the use of insecticides can select gene amplifications causing an increased expression of detoxification enzymes, supporting the usefulness of th...

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Bibliographic Details
Main Authors: Julien Cattel, Chloé Haberkorn, Fréderic Laporte, Thierry Gaude, Tristan Cumer, Julien Renaud, Ian W. Sutherland, Jeffrey C. Hertz, Jean‐Marc Bonneville, Victor Arnaud, Bénédicte Fustec, Sébastien Boyer, Sébastien Marcombe, Jean‐Philippe David
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Evolutionary Applications
Subjects:
Aedes aegypti
carboxylesterase
diagnostic assay
genomic amplification
insecticide resistance
mosquito
Online Access:https://doi.org/10.1111/eva.13177

Internet

https://doi.org/10.1111/eva.13177

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