The Potential for Genotoxicity, Mutagenicity and Endocrine Disruption in Triclosan and Triclocarban Assessed through a Combination of In Vitro Methods

The Potential for Genotoxicity, Mutagenicity and Endocrine Disruption in Triclosan and Triclocarban Assessed through a Combination of In Vitro Methods

Triclosan and Triclocarban, preservatives widely used in cosmetics and other consumer products, underwent evaluation using a battery of new-approach methodologies in vitro (NAMs). Specifically, the Microplate Ames Test (MPF™ Test, Xenometrix, Allschwil, Switzerland) was employed to assess mutagenici...

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Bibliographic Details
Main Authors: Jan Chrz, Markéta Dvořáková, Kristina Kejlová, Danuše Očadlíková, Lada Svobodová, Lukáš Malina, Barbora Hošíková, Dagmar Jírová, Hana Bendová, Hana Kolářová
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Journal of Xenobiotics
Subjects:
genotoxicity/mutagenicity
preservatives
chromosome aberrations
Ames test
Comet assay
endocrine disruption
Online Access:https://www.mdpi.com/2039-4713/14/1/2

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https://www.mdpi.com/2039-4713/14/1/2

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