Design, spectral, molecular modeling, antimitotic, analytical and mechanism studies of phenyl isothiocyanate Girard's T derived metal complexes

Design, spectral, molecular modeling, antimitotic, analytical and mechanism studies of phenyl isothiocyanate Girard's T derived metal complexes

Abstract The ligand N-{[(phenyl amino) thioxomethyl] hydrazino carbonyl methyl} trimethyl ammonium chloride (PTHAC) was prepared by the refluxing phenyl isothiocyanate and Girard-T (trimethyl ammonium-acethydrazide) in a molar ratio (1:1). The metal complexes derived from NiCl2.6H2O, CuCl2.2H2O and...

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Bibliographic Details
Main Authors: Magda A. Akl, Nora A. El Mahdy, Zizi Elbadrawy, Abdelrahman S. El-Zeny, Mohsen M. Mostafa
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Chemistry
Subjects:
Cu(II)
Co(II)
Ni(II)
Girard-T
DFT calculations
Molecular docking
Online Access:https://doi.org/10.1186/s13065-023-01033-x

Internet

https://doi.org/10.1186/s13065-023-01033-x

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