Crowding alters F-actin secondary structure and hydration

Abstract Actin, an important component of eukaryotic cell cytoskeleton, regulates cell shape and transport. The morphology and biochemical properties of actin filaments are determined by their structure and protein-protein contacts. Crowded environments can organize filaments into bundles, but less...

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Bibliographic Details
Main Authors: Xiaobing Chen, Steven J. Roeters, Francis Cavanna, José Alvarado, Carlos R. Baiz
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05274-3