Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers
The amyloid β peptide (Aβ) is a key player in the etiology of Alzheimer disease (AD), yet a systematic investigation of its molecular interactions has not been reported. Here we identified by quantitative mass spectrometry proteins in human brain extract that bind to oligomeric Aβ1-42 (oAβ1-42) and/...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-06-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/28401 |