Phosphorylation of the Archaeal Holliday Junction Resolvase Hjc Inhibits Its Catalytic Activity and Facilitates DNA Repair in Sulfolobus islandicus REY15A

Phosphorylation of the Archaeal Holliday Junction Resolvase Hjc Inhibits Its Catalytic Activity and Facilitates DNA Repair in Sulfolobus islandicus REY15A

Protein phosphorylation is one of the main protein post-translational modifications and regulates DNA repair in eukaryotes. Archaeal genomes encode eukaryotic-like DNA repair proteins and protein kinases (ePKs), and several proteins involved in homologous recombination repair (HRR) including Hjc, a...

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Bibliographic Details
Main Authors: Qihong Huang, Joseph Badys Mayaka, Qing Zhong, Chao Zhang, Guihua Hou, Jinfeng Ni, Yulong Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Microbiology
Subjects:
archaea
protein phosphorylation
protein kinase
homologous recombination repair
holliday junction resolvase
Hjc
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01214/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01214/full

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