Deciphering Structural Determinants in Chondroitin Sulfate Binding to FGF-2: Paving the Way to Enhanced Predictability of Their Biological Functions

Deciphering Structural Determinants in Chondroitin Sulfate Binding to FGF-2: Paving the Way to Enhanced Predictability of Their Biological Functions

Controlling chondroitin sulfates (CSs) biological functions to exploit their interesting potential biomedical applications requires a comprehensive understanding of how the specific sulfate distribution along the polysaccharide backbone can impact in their biological activities, a still challenging...

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Bibliographic Details
Main Authors: Giulia Vessella, José Antonio Vázquez, Jesús Valcárcel, Laura Lagartera, Dianélis T. Monterrey, Agatha Bastida, Eduardo García-Junceda, Emiliano Bedini, Alfonso Fernández-Mayoralas, Julia Revuelta
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Polymers
Subjects:
glycosaminoglycan
chondroitin sulfate
structure-activity relationships
protein interactions
fibroblast growth factor 2
Online Access:https://www.mdpi.com/2073-4360/13/2/313

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https://www.mdpi.com/2073-4360/13/2/313

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