QuilA® adjuvanted Coxevac® sustains Th1-CD8+-type immunity and increases protection in Coxiella burnetii-challenged goats

Abstract Coxevac® is the EMA-approved veterinary vaccine for the protection of cattle and goats against Q fever, a zoonotic bacterial disease due to Coxiella burnetii. Since Coxevac® reduces bacterial shedding and clinical symptoms but does not prevent infection, novel, ready-to-use vaccine formulat...

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Bibliographic Details
Main Authors: Sara Tomaiuolo, Wiebke Jansen, Susana Soares Martins, Bert Devriendt, Eric Cox, Marcella Mori
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00607-z