Metabolomics and metagenomics reveal the impact of γδ T inhibition on gut microbiota and metabolism in periodontitis-promoting OSCC

Metabolomics and metagenomics reveal the impact of γδ T inhibition on gut microbiota and metabolism in periodontitis-promoting OSCC

ABSTRACTDuring the process of periodontitis-promoting oral squamous cell carcinoma (OSCC), the periodontitis microbiota can facilitate OSCC development by activating γδ T cells. Inhibiting γδ T cells through immunotherapy has been shown to significantly alleviate various types of cancer. However, th...

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Bibliographic Details
Main Authors: Wei Wei, Jing Li, Boyu Tang, Ye Deng, Yan Li, Qianming Chen
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mSystems
Subjects:
γδ T
OSCC
metabolomics
metagenomics
microbiota
Online Access:https://journals.asm.org/doi/10.1128/msystems.00777-23

Internet

https://journals.asm.org/doi/10.1128/msystems.00777-23

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