Hepatitis B Virus Covalently Closed Circular DNA Predicts Postoperative Liver Cancer Metastasis Independent of Virological Suppression

Hepatitis B Virus Covalently Closed Circular DNA Predicts Postoperative Liver Cancer Metastasis Independent of Virological Suppression

New antiviral therapies against hepatitis B virus (HBV) focus on the elimination of covalently closed circular DNA (cccDNA). However, traditional cccDNA-specific quantitative PCR (qPCR) has a narrow effective range, hindering a reliable comparison between the levels of biopsy-derived cccDNAs. Collat...

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Bibliographic Details
Main Authors: Chao-Wei Hsu, Yu-De Chu, Ming-Wei Lai, Chih-Lang Lin, Kung-Hao Liang, Yang-Hsiang Lin, Chau-Ting Yeh
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
hepatitis B virus
covalently closed circular DNA
peptide nucleic acid clamping
metastasis
hepatocellular carcinoma
Online Access:https://www.mdpi.com/2072-6694/13/3/538

Internet

https://www.mdpi.com/2072-6694/13/3/538

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