The regulatory role and therapeutic application of pyroptosis in musculoskeletal diseases

Abstract Pyroptosis is a controlled form of inflammatory cell death characterized by inflammasome activation, pore formation, and cell lysis. According to different caspases, pyroptosis can be divided into canonical, non-canonical, and other pathways. The role of pyroptosis in disease development ha...

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Bibliographic Details
Main Authors: Siyu Wang, Hua Wang, Chengyao Feng, Chenbei Li, Zhihong Li, Jieyu He, Chao Tu
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01282-0