CD44v9 Induces Stem Cell-Like Phenotypes in Human Cholangiocarcinoma

CD44v9 Induces Stem Cell-Like Phenotypes in Human Cholangiocarcinoma

Background: Our previous study demonstrated an overexpression of CD44 variant 9 (CD44v9) in human cholangiocarcinoma (CCA) tissues that was associated with inflammation-related tumor development. However, the participation of CD44v9 in cholangiocarcinogenesis remains poorly understood. Therefore, in...

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Bibliographic Details
Main Authors: Nattawan Suwannakul, Ning Ma, Kaoru Midorikawa, Shinji Oikawa, Hatasu Kobayashi, Feng He, Shosuke Kawanishi, Mariko Murata
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cholangiocarcinoma
CD44 variant 9
epithelial-mesenchymal transition
Wnt/β-catenin
cancer stem cell
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00417/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00417/full

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