The Oncogenic and Tumor Suppressive Functions of the Long Noncoding RNA MALAT1: An Emerging Controversy

The Oncogenic and Tumor Suppressive Functions of the Long Noncoding RNA MALAT1: An Emerging Controversy

Long noncoding RNAs are recently emerging as critical factors of tumorigenesis. Originally regarded as a pre-messenger RNA (mRNA) splicing regulator, the long noncoding RNA MALAT1 has been demonstrated to regulate gene transcription by binding histone modification enzymes and transcription factors,...

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Bibliographic Details
Main Authors: Qingjuan Chen, Chenjing Zhu, Yingying Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Genetics
Subjects:
MALAT1
pre-messenger RNA splicing
gene expression
tumorigenesis
cell migration
invasion
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00093/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00093/full

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