Immune transcriptome analysis of COVID-19 patients infected with SARS-CoV-2 variants carrying the E484K escape mutation identifies a distinct gene module

Immune transcriptome analysis of COVID-19 patients infected with SARS-CoV-2 variants carrying the E484K escape mutation identifies a distinct gene module

Abstract Fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) energize the COVID-19 pandemic. While viral infections elicit a conserved immune response, it is not known whether SARS-CoV-2 variants, which display enhanced binding to the ACE2 receptor and reduced neu...

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Bibliographic Details
Main Authors: Hye Kyung Lee, Ludwig Knabl, Manuel Wieser, Anna Mur, August Zabernigg, Jana Schumacher, Sebastian Kapferer, Norbert Kaiser, Priscilla A. Furth, Lothar Hennighausen
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-06752-0

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https://doi.org/10.1038/s41598-022-06752-0

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