Targeting Secreted Protease/Anti-Protease Balance as a Vaccine Strategy against the Helminth <i>Fasciola hepatica</i>

Targeting Secreted Protease/Anti-Protease Balance as a Vaccine Strategy against the Helminth <i>Fasciola hepatica</i>

The liver fluke <i>Fasciola hepatica</i> is an economically important global pathogen of humans and their livestock. To facilitate host invasion and migration, <i>F. hepatica</i> secretes an abundance of cathepsin peptidases but prevents excessive damage to both parasite and...

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Bibliographic Details
Main Authors: Krystyna Cwiklinski, Orla Drysdale, Jesús López Corrales, Yolanda Corripio-Miyar, Carolina De Marco Verissimo, Heather Jewhurst, David Smith, Richard Lalor, Tom N. McNeilly, John P. Dalton
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Vaccines
Subjects:
<i>Fasciola hepatica</i>
sheep
vaccines
protease-anti-protease balance
stefin
Kunitz-type inhibitor
Online Access:https://www.mdpi.com/2076-393X/10/2/155

Internet

https://www.mdpi.com/2076-393X/10/2/155

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