Predicting gene expression state and prioritizing putative enhancers using 5hmC signal
Abstract Background Like its parent base 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC) is a direct epigenetic modification of cytosines in the context of CpG dinucleotides. 5hmC is the most abundant oxidized form of 5mC, generated through the action of TET dioxygenases at gene bodies of act...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-06-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-024-03273-z |