A 4.7-kDa polysaccharide from Panax ginseng suppresses Aβ pathology via mitophagy activation in cross-species Alzheimer’s disease models

A 4.7-kDa polysaccharide from Panax ginseng suppresses Aβ pathology via mitophagy activation in cross-species Alzheimer’s disease models

Alzheimer's disease (AD) is a neurological condition that progresses with age. Amyloid-β (Aβ) aggregation has been suggested to be a key pathogenic process in Alzheimer's disease. Ginseng polysaccharides (GP), the main biologically active components isolated from Panax ginseng C. A. Meyer...

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Bibliographic Details
Main Authors: Shuai Zhang, Fangbing Liu, Jinmeng Li, Chenxu Jing, Jing Lu, Xuenan Chen, Dandan Wang, Donghui Cao, Daqing Zhao, Liwei Sun
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alzheimer’s disease
Amyloid-β
GP4
Caenorhabditis elegans
Cerebral organoid
Mitophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223012404

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http://www.sciencedirect.com/science/article/pii/S0753332223012404

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