Direct Comparison of the Lowest Effect Concentrations of Mutagenic Reference Substances in Two Ames Test Formats

Direct Comparison of the Lowest Effect Concentrations of Mutagenic Reference Substances in Two Ames Test Formats

The Ames assay is the standard assay for identifying DNA-reactive genotoxic substances. Multiple formats are available and the correct choice of an assay protocol is essential for achieving optimal performance, including fit for purpose detection limits and required screening capacity. In the presen...

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Bibliographic Details
Main Authors: Bernhard Rainer, Elisabeth Pinter, Lukas Prielinger, Chiara Coppola, Maricel Marin-Kuan, Benoit Schilter, Silvia Apprich, Manfred Tacker
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Toxics
Subjects:
complex mixtures
mutagenicity
genotoxicity
Ames assay
food contact materials
bacterial reverse mutation
Online Access:https://www.mdpi.com/2305-6304/9/7/152

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https://www.mdpi.com/2305-6304/9/7/152

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