Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies

Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies

Abstract Human monoclonal antibodies (mAbs) against the central repeat and junction domain of Plasmodium falciparum circumsporozoite protein (PfCSP) have been studied extensively to guide malaria vaccine design compared to antibodies against the PfCSP C terminus. Here, we describe the molecular char...

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Bibliographic Details
Main Authors: Opeyemi Ernest Oludada, Giulia Costa, Clare Burn Aschner, Anna S Obraztsova, Katherine Prieto, Caterina Canetta, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller, Rajagopal Murugan, Jean‐Philippe Julien, Elena A Levashina, Hedda Wardemann
Format: Article
Language:English
Published: Springer Nature 2023-04-01
Series:EMBO Molecular Medicine
Subjects:
Affinity maturation
Antibodies
Malaria
PfCSP
Plasmodium
Online Access:https://doi.org/10.15252/emmm.202317454

Internet

https://doi.org/10.15252/emmm.202317454

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