CRISPR/Cas9-Induced Double-Strand Break Repair in Arabidopsis Nonhomologous End-Joining Mutants

CRISPR/Cas9-Induced Double-Strand Break Repair in Arabidopsis Nonhomologous End-Joining Mutants

Double-strand breaks (DSBs) are one of the most harmful DNA lesions. Cells utilize two main pathways for DSB repair: homologous recombination (HR) and nonhomologous end-joining (NHEJ). NHEJ can be subdivided into the KU-dependent classical NHEJ (c-NHEJ) and the more error-prone KU-independent backup...

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Bibliographic Details
Main Authors: Hexi Shen, Gary D. Strunks, Bart J. P. M. Klemann, Paul J. J. Hooykaas, Sylvia de Pater
Format: Article
Language:English
Published: Oxford University Press 2017-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Arabidopsis thaliana
CRISPR/Cas9
double-strand break
KU80
nonhomologous end-joining
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.035204

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.035204

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