Chitosan coatings with distinct innate immune bioactivities differentially stimulate angiogenesis, osteogenesis and chondrogenesis in poly-caprolactone scaffolds with controlled interconnecting pore size

Chitosan coatings with distinct innate immune bioactivities differentially stimulate angiogenesis, osteogenesis and chondrogenesis in poly-caprolactone scaffolds with controlled interconnecting pore size

This study tested whether osseous integration into poly (ε-caprolactone) (PCL) bioplastic scaffolds with fully-interconnecting 155 ± 8 μm pores is enhanced by an adhesive, non-inflammatory 99% degree of deacetylation (DDA) chitosan coating (99-PCL), or further incorporation of pro-inflammatory 83% D...

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Bibliographic Details
Main Authors: Caroline D. Hoemann, Javier Rodríguez González, Jessica Guzmán-Morales, Gaoping Chen, Ebrahim Jalali Dil, Basil D. Favis
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-04-01
Series:Bioactive Materials
Subjects:
Bone tissue engineering
Cartilage tissue engineering
Hematoma
Chitosan
Angiogenesis
Osteogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21004291

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X21004291

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