Filamin, a synaptic organizer in Drosophila, determines glutamate receptor composition and membrane growth

Filamin is a scaffolding protein that functions in many cells as an actin-crosslinker. FLN90, an isoform of the Drosophila ortholog Filamin/cheerio that lacks the actin-binding domain, is here shown to govern the growth of postsynaptic membrane folds and the composition of glutamate receptor cluster...

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Bibliographic Details
Main Authors: GaYoung Lee, Thomas L Schwarz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/19991