Upregulation of microRNA-125b-5p alleviates acute liver failure by regulating the Keap1/Nrf2/HO-1 pathway

Upregulation of microRNA-125b-5p alleviates acute liver failure by regulating the Keap1/Nrf2/HO-1 pathway

BackgroundAcute liver failure (ALF) and acute-on-chronic liver failure (ACLF) are the two most common subtypes of liver failure. They are both life-threatening clinical problems with high short-term mortality. Although liver transplantation is an effective therapeutic, its application is limited due...

Full description

Bibliographic Details
Main Authors: Ya-Chao Tao, Yong-Hong Wang, Meng-Lan Wang, Wei Jiang, Dong-Bo Wu, En-Qiang Chen, Hong Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
acute liver failure
acute-on-chronic liver failure
microRNA-125b-5p
Kelch-like ECH-associated protein 1
high-throughput sequencing
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.988668/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.988668/full

Similar Items