Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles

A series of new morpholinylchalcones was prepared and then used as building blocks for constructing a series of 7-morpholino-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones via their reaction with 6-aminothiouracil. The latter thiones reacted with the appropriate hydrazonoyl chloride to give t...

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Bibliographic Details
Main Authors: Zeinab A. Muhammad, Mastoura M. Edrees, Rasha A. M. Faty, Sobhi M. Gomha, Seham S. Alterary, Yahia N. Mabkhot
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/22/7/1211