Molecular cloning and characterization of the family of feline leucine-rich glioma-inactivated (LGI) genes, and mutational analysis in familial spontaneous epileptic cats

Molecular cloning and characterization of the family of feline leucine-rich glioma-inactivated (LGI) genes, and mutational analysis in familial spontaneous epileptic cats

Abstract Background Leucine-rich glioma-inactivated (LGI) proteins play a critical role in synaptic transmission. Dysfunction of these genes and encoded proteins is associated with neurological disorders such as genetic epilepsy or autoimmune limbic encephalitis in animals and human. Familial sponta...

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Bibliographic Details
Main Authors: Yoshihiko Yu, Daisuke Hasegawa, Aki Fujiwara-Igarashi, Yuji Hamamoto, Shunta Mizoguchi, Takayuki Kuwabara, Michio Fujita
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Veterinary Research
Subjects:
Feline
Epilepsy
Lgi
Cloning and sequence analysis
Molecular characterization
Online Access:http://link.springer.com/article/10.1186/s12917-017-1308-9

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http://link.springer.com/article/10.1186/s12917-017-1308-9

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