Human papillomavirus-16 E7 interacts with glutathione S-transferase P1 and enhances its role in cell survival.

Human papillomavirus-16 E7 interacts with glutathione S-transferase P1 and enhances its role in cell survival.

BACKGROUND:Human Papillomavirus (HPV)-16 is a paradigm for "high-risk" HPVs, the causative agents of virtually all cervical carcinomas. HPV E6 and E7 viral genes are usually expressed in these tumors, suggesting key roles for their gene products, the E6 and E7 oncoproteins, in inducing mal...

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Main Authors: Anna M Mileo, Claudia Abbruzzese, Stefano Mattarocci, Emanuele Bellacchio, Paola Pisano, Antonio Federico, Vittoria Maresca, Mauro Picardo, Alessandra Giorgi, Bruno Maras, M Eugenia Schininà, Marco G Paggi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2758704?pdf=render

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http://europepmc.org/articles/PMC2758704?pdf=render

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