Explaining Redundancy in CDK-Mediated Control of the Cell Cycle: Unifying the Continuum and Quantitative Models

In eukaryotes, cyclin-dependent kinases (CDKs) are required for the onset of DNA replication and mitosis, and distinct CDK–cyclin complexes are activated sequentially throughout the cell cycle. It is widely thought that specific complexes are required to traverse a point of commitment to the cell cy...

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Bibliographic Details
Main Authors: Daniel Fisher, Liliana Krasinska
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/13/2019