Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules

Direct Generation of Human Neuronal Cells from Adult Astrocytes by Small Molecules

Astrocytes, due to the proximity to neuronal lineage and capability to proliferate, are ideal starting cells to regenerate neurons. Human fetal astrocytes have been successfully converted into neuronal cells by small molecules, which offered a broader range of further applications than transcription...

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Bibliographic Details
Main Authors: Longfei Gao, Wuqiang Guan, Min Wang, Huihan Wang, Jiali Yu, Qing Liu, Binlong Qiu, Yongchun Yu, Yifang Ping, Xiuwu Bian, Li Shen, Gang Pei
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Stem Cell Reports
Subjects:
human adult astrocytes
neuronal cells
small molecules
transdifferentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117300292

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http://www.sciencedirect.com/science/article/pii/S2213671117300292

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