Function and Regulation of Yeast Ribonucleotide Reductase: Cell Cycle, Genotoxic Stress, and Iron Bioavailability

Function and Regulation of Yeast Ribonucleotide Reductase: Cell Cycle, Genotoxic Stress, and Iron Bioavailability

Ribonucleotide reductases (RNRs) are essential enzymes that catalyze the reduction of ribonucleotides to desoxyribonucleotides, thereby providing the building blocks required for de novo DNA biosynthesis. The RNR function is tightly regulated because an unbalanced or excessive supply of deoxyribonuc...

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Bibliographic Details
Main Authors: Nerea Sanvisens, Rosa de Llanos, Sergi Puig
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Biomedical Journal
Subjects:
cell cycle
genotoxic stress
iron deficiency
ribonucleotide reductase
Saccharomyces cerevisiae
yeast
Online Access:http://www.biomedj.org/article.asp?issn=2319-4170;year=2013;volume=36;issue=2;spage=51;epage=58;aulast=Sanvisens

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http://www.biomedj.org/article.asp?issn=2319-4170;year=2013;volume=36;issue=2;spage=51;epage=58;aulast=Sanvisens

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