Targeting HSP90 as a Novel Therapy for Cancer: Mechanistic Insights and Translational Relevance

Targeting HSP90 as a Novel Therapy for Cancer: Mechanistic Insights and Translational Relevance

Heat shock protein (HSP90), a highly conserved molecular chaperon, is indispensable for the maturation of newly synthesized poly-peptides and provides a shelter for the turnover of misfolded or denatured proteins. In cancers, the client proteins of HSP90 extend to the entire process of oncogenesis t...

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Bibliographic Details
Main Authors: Jian Zhang, Houde Li, Yu Liu, Kejia Zhao, Shiyou Wei, Eric T. Sugarman, Lunxu Liu, Gao Zhang
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
heat shock protein 90
INHIBITORS
cancer therapeutics
translational relevance
Online Access:https://www.mdpi.com/2073-4409/11/18/2778

Internet

https://www.mdpi.com/2073-4409/11/18/2778

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