Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets

Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets

Ghrelin receptor, a growth hormone secretagogue receptor (GHS-R), is expressed in the pancreas. Emerging evidence indicates that GHS-R is involved in the regulation of glucose-stimulated insulin secretion (GSIS), but the mechanism by which GHS-R regulates GSIS in the pancreas is unclear. In this stu...

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Bibliographic Details
Main Authors: Geetali Pradhan, Jong Han Lee, Chia-Shan Wu, Hongying Wang, Ligen Lin, Taraka Donti, Brett H. Graham, Arun S. Rajan, Ashok Balasubramanyam, Susan L. Samson, Shaodong Guo, Yuxiang Sun
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomolecules
Subjects:
growth hormone secretagogue receptor (GHS-R)
glucose-stimulated insulin secretion (GSIS)
glucose transporter 2 (<i>Glut2</i>)
pancreatic and duodenal homeobox 1 (Pdx1)
insulin
islets
Online Access:https://www.mdpi.com/2218-273X/12/3/407

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https://www.mdpi.com/2218-273X/12/3/407

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