Paradoxical Effect of Chloroquine Treatment in Enhancing Chikungunya Virus Infection

Paradoxical Effect of Chloroquine Treatment in Enhancing Chikungunya Virus Infection

Since 2005, Chikungunya virus (CHIKV) re-emerged and caused numerous outbreaks in the world, and finally, was introduced into the Americas in 2013. The lack of CHIKV-specific therapies has led to the use of non-specific drugs. Chloroquine, which is commonly used to treat febrile illnesses in the tro...

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Bibliographic Details
Main Authors: Pierre Roques, Simon-Djamel Thiberville, Laurence Dupuis-Maguiraga, Fok-Moon Lum, Karine Labadie, Frédéric Martinon, Gabriel Gras, Pierre Lebon, Lisa F. P. Ng, Xavier de Lamballerie, Roger Le Grand
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Viruses
Subjects:
alphavirus
chikungunya
chloroquine
monocyte-macrophage
macaque
Online Access:http://www.mdpi.com/1999-4915/10/5/268

Internet

http://www.mdpi.com/1999-4915/10/5/268

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