Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues

Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues

IntroductionRecent advances in human cardiac 3D approaches have yielded progressively more complex and physiologically relevant culture systems. However, their application in the study of complex pathological processes, such as inflammation and fibrosis, and their utility as models for drug developm...

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Bibliographic Details
Main Authors: Jasmeet S. Reyat, Alessandro di Maio, Beata Grygielska, Jeremy Pike, Samuel Kemble, Antonio Rodriguez-Romero, Christina Simoglou Karali, Adam P. Croft, Bethan Psaila, Filipa Simões, Julie Rayes, Abdullah O. Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
3D cardiac microtissues
induced pluripotent stem cells
tissue engineering
cardiac fibrosis
cardiomyocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1156759/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1156759/full

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