Overexpression of hypoxia-inducible factor 1α and excessive vascularization in the peri-implantation endometrium of infertile women with chronic endometritis

Overexpression of hypoxia-inducible factor 1α and excessive vascularization in the peri-implantation endometrium of infertile women with chronic endometritis

ObjectiveChronic endometritis (CE) contributes to impaired endometrial receptivity and is closely associated with poor in vitro fertilization (IVF) outcomes. However, the mechanisms underlying CE are unclear. Here, we investigated the role of the hypoxic microenvironment and endometrial vascularizat...

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Bibliographic Details
Main Authors: Zhenteng Liu, Xuemei Liu, Fenghua Li, Yuxia Sun, Lili Yu, Wei Zhang, Ping Zhu, Ding Ma, Xinrong Wang, Shoucui Lai, Hongchu Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
chronic endometritis
in vitro fertilization
hypoxia-inducible factor 1α
VEGFA
infertility
endometrial receptivity
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1001437/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.1001437/full

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