Alzheimer’s pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome

Alzheimer’s pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome

Abstract Background Traumatic encephalopathy syndrome (TES) is a clinical phenotype sensitive but non-specific to underlying chronic traumatic encephalopathy (CTE) neuropathology. However, cognitive symptoms of TES overlap with Alzheimer’s disease (AD), and features of AD pathology like beta-amyloid...

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Bibliographic Details
Main Authors: Breton M. Asken, Jeremy A. Tanner, Leslie S. Gaynor, Lawren VandeVrede, William G. Mantyh, Kaitlin B. Casaletto, Adam M. Staffaroni, Corrina Fonseca, Ranjani Shankar, Harli Grant, Karen Smith, Argentina Lario Lago, Haiyan Xu, Renaud La Joie, Yann Cobigo, Howie Rosen, David C. Perry, Julio C. Rojas, Bruce L. Miller, Raquel C. Gardner, Kevin K. W. Wang, Joel H. Kramer, Gil D. Rabinovici
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Traumatic encephalopathy syndrome
Chronic traumatic encephalopathy
Amyloid
PET
Plasma
Biomarker
Online Access:https://doi.org/10.1186/s13195-023-01275-w

Internet

https://doi.org/10.1186/s13195-023-01275-w

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