Klf10 is involved in extracellular matrix calcification of chondrocytes alleviating chondrocyte senescence

Abstract Osteoarthritis (OA) is a chronic degenerative disease resulting joint disability and pain. Accumulating evidences suggest that chondrocyte extracellular matrix calcification plays an important role in the development of OA. Here, we showed that Krüppel-like factor 10 (Klf10) was involved in...

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Bibliographic Details
Main Authors: Rong Peng, Jie Shang, Ning Jiang, Hsu Chi-Jen, Yu Gu, Baizhou Xing, Renan Hu, Biao Wu, Dawei Wang, Xianghe Xu, Huading Lu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-023-04666-7